ISSN: 1300-8773
E-ISSN: 1304-4591
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Hypoparathyroidism as a cause of recurrent seizures
Murat Alemdar
Article Type: A Case Report

Metabolic imbalances are among the most common causes of recurrent seizures. Herein, we aimed to report a 16 year-old man with idiopathic hypoparathyroidism presented to our outpatient clinic with recurrent seizures having been introduced antiepileptic drug five months ago. Upon focal to bilateral tonic– clonic seizure with the duration of 2-3 minutes three times in a month, he had applied to a pediatrician. Carbamazepine treatment had been introduced with suspicion of epilepsy, but his seizures had continued with same intervals and durations. The onset of the first seizure in an unexpected age and focal seizure characteristics of the patient referred to our outpatient clinic were evocative features of a probable underlying disorder. Hypocalcemia and hyperphosphatemia were detected on laboratory examinations. Serum parathyroid hormone level was measured as 0.2 ng / L (8-24 ng / L) with normal vitamin D level. Computed tomography of brain revealed seizures symmetrical cerebral calcifications. We considered his episodes as symptomatic seizures. After calcium and vitamin D replacement, he got completely seizure free. The history of this case highlights the importance of searching the secondary causes of acute symptomatic seizures other than epilepsy, in particular for the patients having the first seizure in an unexpected age with focal characteristics. A complete cessation of seizures could be achieved with the control of serum calcium levels in patients with hypoparathyroidism.

Key words: hypoparathyroidism, hypocalcemia, seizure, epilepsy

New Sempozyum Journal 2019; 57(3):23-25